入侵：ACE抑制剂
新冠病毒入侵时会破坏ACE2蛋白，打破“ACE vs ACE2”平衡。沙坦或普利类高血压药物可以抑制ACE或抑制血管紧张素，也许可以避免细胞因为ACE2受损而被破坏，缓解病
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今天有一篇论文回顾了 使用不同高血压药物的武汉患者的新冠治疗效果，发现使用ace抑制剂类高血压药的患者，重症率和死亡率都要低一一些。
Among COVID-19 patients with hypertension, those received either ARBs/ACEIs or non-ARBs/ACEIs had comparable blood pressure. However, ARBs/ACEIs group had significantly lower concentrations of CRP (p=0.049) and procalcitonin (PCT, p=0.008). Furthermore, much lower proportion of critical patients (9.3% vs 22.9%; p=0.061), and a lower death rate (4.7% vs 13.3%; p=0.216) were observed in ARBs/ACEIs group than non-ARBs/ACEIs group, although these differences failed to reach statistical significance. Our findings thus support the use of ARBs/ACEIs in COVID-19 patients with preexisting hypertension.
